Szerkesztő:Zsalab2

Balázs Győrffy MD, PhD

Harvard-MIT Health Sciences and Technology, Enders 150.6, 300 Longwood Avenue, 02114 MA, Boston, USA

Tudományos közleményeim:

1. Gosepath EM, Eckstein N, Hamacher A, Servan K, Jonquieres G, Royer HD, Lage H, Gyorffy B, Kassack MU. Acquired cisplatin resistance in the head-neck cancer cell line Cal27 is associated with decreased DKK1 expression and can partially be reversed by overexpression of DKK1. Int J Cancer, 2008, in press

2. Gyorffy B, Dietel M, Fekete T, Lage H. A snap shot of microarray-generated gene expression signatures associated with ovarian carcinoma, Int J Gynecol Cancer, 2008, in press

3. Gyorffy B, Galamb O, Sipos F, Spisák S, Németh AM, Miheller P, Tulassay Z, Dinya E, Molnár B. Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature Dis Markers, 2008, in press

4. Galamb O, Gyorffy B, Sipos F, Dinya E, Krenács T, Berczi L, Szõke D, Spisák S, Solymosi N, Németh AM, Juhász M, Molnár B, Tulassay Z. Helicobacter pylori and antrum erosion-specific gene expression patterns: the discriminative role of CXCL13 and VCAM1 transcripts. Helicobacter. 2008 Apr;13(2):112-26.

5. Podmaniczky E, Varga J, Barta P, Magyar P, Gyorffy B. The role of CD4+CD25+ regulatory T cells and inefficient immune response in the pathogensis of lung cancer, Medicina Thoracalis, 2007.

6. Fekete A, Szabo AJ, Banki NF, Gyorffy B, Tulassay T, Vasarhelyi B. Pooling analysis of genetic data: heat shock protein HSPA1B (1267)G allele: a possible selection factor for civilization diseases?! Heat Shock Proteins: New Research, Nova Science Publishers, Inc. 2008

7. Munkácsy G, Tulassay Z, Gyorffy B. RNA interference and its clinical applications. Orv Hetil. 2007 Nov 25;148(47):2235-40.

8. Szoke D, Gyorffy A, Surowiak P, Tulassay Z, Dietel M, Gyorffy B. Identification of consensus genes and key regulatory elements in 5-fluorouracil resistance in gastric and colon cancer. Onkologie. 2007 Sep;30(8-9):421-6.

9. Gyorffy B, Rosivall L, Prohaszka Z, Falus A, Fust G, Munkacsy G, Tulassay T. The Danubian Biobank Initiative: synchronizing the biobanking activities of the Danube universities Orv Hetil. 2007 Oct 21;148(42):1999-2002.

10. Galamb O, Gyorffy B, Sipos F, Spisak S, Nemeth AM, Miheller P, Dinya E, Molnar B, Tulassay Z. Identification of colorectal cancer, adenoma, and inflammatory bowel disease specific gene expression patterns using whole genomic oligonucleotide microarray system. Orv Hetil. 2007 Nov 4;148(44):2067-79.

11. Gyorffy A, Surowiak P, Tulassay Z, Gyorffy B. Highly expressed genes are associated with inverse antisense transcription in mouse. J Genet. 2007 Aug;86(2):103-9.

12. Schafer R, Tchernitsa OI, Gyorffy B, Serra V, Abdul-Ghani R, Lund P, Sers C. Functional transcriptomics: an experimental basis for understanding the systems biology for cancer cells. Adv Enzyme Regul. 2007;47:41-62.

13. Gyorffy B, Lage H. A Web-Based Data Warehouse on Gene Expression in Human Malignant Melanoma. J Invest Dermatol. 2007 Feb;127(2):394-9.

14. Gyorffy B. Resistance-Associated Signatures in Breast Cancer, Targeted Therapies in Oncology, Recent Results in Cancer Research, Springer-Verlag Berlin Heidelberg, 2007;176:37-50.

15. Vasarhelyi B, Bencsik P, Szmolenszky A, Molnar MJ, Gyorffy B, Kosztolanyi G, Tulassay T, Falus A. Internet-based biobank-registers in Hungary, Orv Hetil. 2007 May 20;148(20):939-43.

16. Gyorffy A, Tulassay Z, Surowiak P, Gyorffy B. Computational analysis reveals 43% antisense transcription in 1182 transcripts in mouse muscle, DNA Sequence 2006 Dec;17(6):422-30.

17. Nagy GR, Gyorffy B, Galamb O, Molnar B, Nagy B, Papp Z. Use of routinely collected amniotic fluid for whole-genome expression analysis of polygenic disorders. Clin Chem. 2006 Nov;52(11):2013-20.

18. Tegze B, Tulassay Z, Gyorffy B. Chemotherapy agents, response rates and mechanisms of resistance in the therapy of the colorectal carcinoma Magy Onkol. 2006;50(4):315-23.

19. Surowiak P, Materna V, Gyorffy B, Matkowski R, Wojnar A, Maciejczyk A, Paluchowski P, Dzięgiel P, Pudełko M, Kornafel J, Dietel M, Kristiansen G, Zabel M, Lage H. Mutlivariate analysis of estrogen receptor alpha, pS2, metallothionein and CD24 expression in invasive breast cancers. Brit J Cancer, 2006 Aug 7;95(3):339-46.

20. Gyorffy A, Vasarhelyi B, Szoke D, Dietel M, Tulassay T, Gyorffy B. Comparative promoter analysis of doxorubicin resistance associated genes suggests e47 as a key regulatory element. Anticancer Res, 2006 Jul-Aug;26(4B):2971-6.

21. Gyorffy A, Makai D, Gyorffy B, Harsanyi G, Tulassay Z. Microelectrodes and their application in diagnostic medicine Orv Hetil. 2006 Sep 3;147(35):1703-8.

22. Surowiak P, Suchocki S, Gyorffy B, Gansukh T, Wojnar A, Maciejczyk A, Pudełko M, Zabel M. Stromal myofibroblasts in breast cancer: relations between their occurrence, tumor grade and expression of some tumor markers. Folia Histochem Cytobiol, 2006;44(2):111-6.

23. Gyorffy B, Serra V, Materna V, Schafer R, Dietel M, Schadendorf D, Lage H. Analysis of gene expression profiles in melanoma cells with acquired resistance against antineoplastic drugs. Melanoma Res. 2006 Apr;16(2):147-155.

24. Gyorffy B, Surowiak P, Kiesslich O, Denkert C, Schafer R, Dietel M, Lage H. Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations. Int J Cancer. 2006 Apr 1;118(7):1699-712.

25. Abdul-Ghani R, Serra V, Gyorffy B, Jurchott K, Solf A, Dietel M, Schafer R. The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1. Oncogene. 2006 Mar 16;25(12):1743-52.

26. Vannay A, Vasarhelyi B, Kornyei M, Treszl A, Kozma G, Gyorffy B, Tulassay T, Sulyok E. Single-nucleotide polymorphisms of VEGF gene are associated with risk of congenital valvuloseptal heart defects. Am Heart J. 2006 Apr;151(4):878-81.

27. Vasarhelyi B, Cseh A, Kocsis I, Treszl A, Gyorffy B, Rigo J Jr. Three mechanisms in the pathogenesis of pre-eclampsia suggested by over-represented transcription factor-binding sites detected with comparative promoter analysis. Mol Hum Reprod. 2006 Jan;12(1):31-4.

28. Gyorffy B, Serra V, Jürchott K, Abdul-Ghani R, Garber M, Stein U, Petersen I, Lage H, Dietel M, Schäfer R: Prediction of Doxorubicin Sensitivity in Breast Tumors Based on Gene Expression Profiles of Drug Resistant Cell Lines Correlates with Patient Survival, Oncogene. 2005;24(51):7542-51.

29. Gyorffy B, Surowiak P, Lage H: Application of Microarrays for the Prediction of Therapy Response in Breast Cancer, Cancer Genomics and Proteomics, 2005,2:255-264.

30. Surowiak P, Matkowski R, Materna V, Gyorffy B, Wojnar A, Pudelko M, Dziegiel P, Kornafel J, Zabel M. Elevated metallothionein (MT) expression in invasive ductal breast cancers predicts tamoxifen resistance. Histol Histopathol. 2005 Oct;20(4):1037-44.

31. Gyorffy A, Gyorffy B, Molnár B, Tulassay Zs: A hibridizáció és alkalmazása DNS array rendszerekben, Orv Hetil. 2005;146(27):1447-52.

32. Gyorffy B, Gyorffy A, Tulassay Zs: A “multiple testing” problémája és a genomiális kísérletekre alkalmazott megoldások, Orv Hetil, 2005;146(12):559-563.

33. Kocsis I, Vásárhelyi B, Gyorffy A, Gyorffy B: Reanalysis of genotype distributions published in Neurology between 1999 and 2002, Neurology, 2004 Jul 27;63(2):357-8.

34. Kocsis I, Gyorffy B, Vásárhelyi B:Examination of Hardy-Weinberg equilibrium in papers of Kidney International: an underused tool, Kidney Int, 2004 May;65(5):1956-1958.

35. Gyorffy B, Kocsis I, Vásárhelyi B: Missed calculations and new conclusions: re-calculation of genotype distribution data published in J Invest Dermatol, 1998-2003, J Invest Dermatol, 2004 Mar;122(3):644-6.

36. Gyorffy B, Kocsis I, Vásárhelyi B: Biallelic genotype distributions in papers published in Gut between 1998 and 2003: altered conclusions after re-calculating the Hardy-Weinberg equilibrium, Gut, 2004 Apr;53(4):614-5.

37. Németh É, Vásárhelyi B, Gyorffy B, Kocsis I: Prevalence of unreported skewness of genotype distributions in papers published in Critical Care Medicine between 1999 and 2003. Crit Care Med, 2004 Jun;32(6):1431-3.

38. Bardóczy Zs, Gyorffy B, Kocsis I, Vásárhelyi B:Re-calculated Hardy-Weinberg values in papers published in Atherosclerosis between 1995 and 2003. Atherosclerosis 2004 Mar;173(1):141-3.

39. Gyorffy B: Statisztikai módszerek nagyfelbontású array rendszerek kiértékelésére, Klin Kisérl Lab Med, 2003;30(4):135-139.

40. Gyorffy B, Szabó A, Vásárhelyi B:A D-vitamin receptor genetikai polimorfizmusok populációgenetikai összefüggései klinikai kórállapotokkal. Orv Hetil, 2003, 144(41):2011-2015.

41. Gyorffy B, Vásárhelyi B, Krikovszky D, Madácsy L, Tordai A, Tulassay T, Szabó A: Gender-specific association of vitamin D receptor polymorphism combinations with type 1 diabetes mellitus. Eur J Endocrinol 2002 Dec;147(6):803-8.